DIO2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16804955	Proteintech 26513-1-AP-20UL	20 μL
16894945	Proteintech 26513-1-AP-150UL	150 μL

Description

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3′,5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3′ UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence , which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

• Antigen: DIO2
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q92813, Q9Z1Y9
• Gene ID (Entrez): 13371, 1734
• Immunogen: DIO2 Fusion Protein Ag24119
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DIO2

• Concentration: 0.4 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: 5DII, D2, DIO2, DIOII, ITDI2, SelY, TXDI2, Type 2 DI, Type II 5 deiodinase
• Gene Symbols: DIO2
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody