Diethyl malonate, 99%, Thermo Scientific Chemicals

Product Code	Brand	Quantity
11452837	Thermo Scientific Alfa Aesar A15468.36	500 g
11462837	Thermo Scientific Alfa Aesar A15468.0E	2500 g
11472837	Thermo Scientific Alfa Aesar A15468.0C	10,000 g

Description

Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethyl malonate is used in organic synthesis for the preparation of alpha-aryl malonates, mono-substituted and di-substituted acetic acid, barbiturates and artificial flavorings. It is also involved in the synthesis of pharmaceuticals like chloroquine, butazolidin and barbital. It acts as intermediate in the synthesis of vitamin B1, vitamin B6, non-steroidal anti-inflammatory agents agrochemicals and perfumes. In Knoevenagel condensation reaction, it reacts with benzaldehyde to get diethyl benzylidenemalonate.

Solubility
Miscible with ethyl alcohol, ether, chloroform and benzene. Slightly miscible with water.

Notes
Incompatible with acids, bases, oxidizing agents and reducing agents.

Chemical Identifiers

• CAS: 105-53-3
• Molecular Weight (g/mol): 160.169
• InChI Key: IYXGSMUGOJNHAZ-UHFFFAOYSA-N
• PubChem CID: 7761
• SMILES: CCOC(=O)CC(=O)OCC

• Molecular Formula: C7H12O4
• MDL Number: MFCD00009195
• Synonym: diethyl malonate, malonic ester, propanedioic acid, diethyl ester, dicarbethoxymethane, malonic acid, diethyl ester, carbethoxyacetic ester, malonic acid diethyl ester, 1,3-diethyl propanedioate, ethyl propanedioate, ethyl malonate van
• IUPAC Name: diethyl propanedioate

Specifications

• CAS: 105-53-3
• Density: 1.055
• Flash Point: 90°C (194°F)
• Molecular Formula: C7H12O4
• MDL Number: MFCD00009195
• Merck Index: 14,3823
• Solubility Information: Miscible with ethyl alcohol,ether,chloroform and benzene. Slightly miscible with water.
• SMILES: CCOC(=O)CC(=O)OCC
• Molecular Weight (g/mol): 160.169
• Formula Weight: 160.17
• Physical Form: Liquid

• Melting Point: °C to 50°C
• Boiling Point: 198°C to 200°C
• Assay Percent Range: 99%
• Refractive Index: 1.414
• Beilstein: 774687
• Synonym: diethyl malonate, malonic ester, propanedioic acid, diethyl ester, dicarbethoxymethane, malonic acid, diethyl ester, carbethoxyacetic ester, malonic acid diethyl ester, 1,3-diethyl propanedioate, ethyl propanedioate, ethyl malonate van
• InChI Key: IYXGSMUGOJNHAZ-UHFFFAOYSA-N
• IUPAC Name: diethyl propanedioate
• PubChem CID: 7761
• Percent Purity: 99%
• Chemical Name or Material: Diethyl Malonate

Safety and Handling

P210-P280-P370+P378q-P501c

H227

missing translation for 'einecsNumber' : 203-305-9

missing translation for 'rtecsNumber' : OO0700000

missing translation for 'tsca' : Yes

Recommended Storage : Ambient temperatures

RUO – Research Use Only