DGKQ Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16877884	Proteintech 17885-1-AP-20UL	20 μL
16867884	Proteintech 17885-1-AP-150UL	150 μL

Description

Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4, 5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.

Specifications

• Antigen: DGKQ
• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Rat, Human, Mouse
• Gene Accession No.: P52824, Q6P5E8
• Gene ID (Entrez): 100361138, 110524, 1609
• Immunogen: DGKQ Fusion Protein Ag11938
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: DGKQ

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: DAG kinase theta, DAGK, DAGK4, DAGK7, DGK theta, DGKQ, Diacylglycerol kinase theta, Diglyceride kinase theta
• Gene Symbols: Dgkq
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody