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Co 101244 hydrochloride, Tocris Bioscience™
GluN2B-selective NMDA antagonist
£146.08 - £473.65
Chemical Identifiers
| CAS | 193356-17-1 |
|---|---|
| Molecular Formula | C21H28ClNO3 |
| Molecular Weight (g/mol) | 377.909 |
| InChI Key | WFFZHKKSIDENAJ-UHFFFAOYSA-N |
| Synonym | co 101244 hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl piperidin-4-ol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol mono hydrochloride, d08nrh, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol monohydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-hydroxy-4-4-methylbenzyl piperidine hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4hydroxy-4-4-methylbenzyl piperidine hydrochloride |
| PubChem CID | 6918426 |
| IUPAC Name | 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride |
| SMILES | CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18064172
|
Tocris Bioscience
2456/10 |
10 mg |
£146.08
10mg |
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|
18034592
|
Tocris Bioscience
2456/50 |
50 mg |
£473.65
50mg |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Novel, potent and selective antagonist of GluN2B (formally NR2B)-containing NMDA receptors (IC50 values are 0.043, > 100 and > 100 μM for GluN1A/2B (NR1A/2B), GluN1A/2A (NR1A/2A) and GluN1A/2C (NR1A/2C) subunit combinations respectively). Displays neuroprotective effects in vivo and in vitro.Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.
Chemical Identifiers
| 193356-17-1 | |
| 377.909 | |
| co 101244 hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl piperidin-4-ol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol mono hydrochloride, d08nrh, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol monohydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-hydroxy-4-4-methylbenzyl piperidine hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4hydroxy-4-4-methylbenzyl piperidine hydrochloride | |
| 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride |
| C21H28ClNO3 | |
| WFFZHKKSIDENAJ-UHFFFAOYSA-N | |
| 6918426 | |
| CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl |
Specifications
| 193356-17-1 | |
| co 101244 hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl piperidin-4-ol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol mono hydrochloride, d08nrh, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol monohydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-4-methylphenyl methyl-4-piperidinol hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4-hydroxy-4-4-methylbenzyl piperidine hydrochloride, 1-2-4-hydroxyphenoxy ethyl-4hydroxy-4-4-methylbenzyl piperidine hydrochloride | |
| CC1=CC=C(C=C1)CC2(CCN(CC2)CCOC3=CC=C(C=C3)O)O.Cl | |
| 377.909 | |
| 377.91 | |
| Co 101244 hydrochloride |
| C21H28ClNO3 | |
| WFFZHKKSIDENAJ-UHFFFAOYSA-N | |
| 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-methylphenyl)methyl]piperidin-4-ol;hydrochloride | |
| 6918426 | |
| >99% |
Safety and Handling
Recommended Storage : Store at +4°C