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Thermo Scientific™ Clostridium Difficile Selective Agar
Description
Isolate, identify and differentiate Clostridium difficile using Thermo Scientific™ Clostridium Difficile Selective Agar, a selective medium with two key components to inhibit non-target organisms.
Selective agents D-cycloserine (500μg/mL) and cefoxitin (16μg/mL) used in the formulation inhibit growth of the majority of Enterobacteriaceae, as well as Streptococcus fecalis, staphylococci, Gram-negative non-sporing anaerobic bacilli, and Clostridium species (except Clostridium difficile), which may be found in large numbers in fecal samples.
Clostridium difficile is a toxin-producing, sporeforming anaerobic gram-positive rod, which causes gastrointestinal infections ranging in severity from asymptomatic colonization to severe diarrhea, pseudomembranous colitus (PMC), toxic megacolon, colonic perforaton, and death. A reduction of the normal microbial flora in the colon, usually caused by antibiotic therapy, allows overgrowth of C. difficile. Most pathogenic strains of C. difficile produce two toxins, toxin A (enterotoxin) and toxin B (cytotoxin), which are the main virulence factors for the organism. An emerging strain of C. difficile contains an additional binary toxin (CDT) believed to be a marker of increased virulence. This strain is missing a gene that regulates production of toxin A and B and has acquired high-level resistance to fluoroquinolone antibiotics.
Not all products are available for sale in all territories. Please inquire.
Remel™ and Oxoid™ products are now part of the Thermo Scientific brand, combining powerful manual, semi-automated and fully automated test products and a comprehensive line of media and diagnostic products to offer a complete, end-to-end solution to quickly deliver the products you need and the quality results your laboratory depends on.
Clostridium difficile is a toxin-producing, sporeforming anaerobic gram-positive rod, which causes gastrointestinal infections ranging in severity from asymptomatic colonization to severe diarrhea, pseudomembranous colitus (PMC), toxic megacolon, colonic perforaton, and death. A reduction of the normal microbial flora in the colon, usually caused by antibiotic therapy, allows overgrowth of C. difficile. Most pathogenic strains of C. difficile produce two toxins, toxin A (enterotoxin) and toxin B (cytotoxin), which are the main virulence factors for the organism. An emerging strain of C. difficile contains an additional binary toxin (CDT) believed to be a marker of increased virulence. This strain is missing a gene that regulates production of toxin A and B and has acquired high-level resistance to fluoroquinolone antibiotics.
Not all products are available for sale in all territories. Please inquire.
Remel™ and Oxoid™ products are now part of the Thermo Scientific brand, combining powerful manual, semi-automated and fully automated test products and a comprehensive line of media and diagnostic products to offer a complete, end-to-end solution to quickly deliver the products you need and the quality results your laboratory depends on.
Specifications
Specifications
| Color | Ruby red, opaque |
| Content And Storage | 2°C to 10°C |
| Description | Clostridium Difficile Selective Agar |
| Format | 90mm Monoplate |
| Manufacturing Origin | United Kingdom |
| Product Type | Agar |
| Fill Weight | 19.5g ± 1.0g |
| Packaging Type | Flow Wrapped - Single Layer |
| Quantity | 10/Pk. |
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