Invitrogen™ Chemerin Monoclonal Antibody (D2), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17970343	Invitrogen™ MA550909	200 μL
17910863	Invitrogen™ MA550910	20 μL

Description

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.

Specifications

• Antigen: Chemerin
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene ID (Entrez): 297073
• Immunogen: Recombinant Rat CHEM protein, Ser25-Gly152 (Accession #Q5BK77).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

• Clone: D2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Rat
• Gene Alias: 0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
• Gene Symbols: Rarres2
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: Rarres2