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  5. Tocris Bioscience™ CH 223191

Tocris Bioscience™ CH 223191

Product Code. 18075892
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50 mg
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18075892 50 mg 50mg
18004132 10 mg 10mg
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Product Code. 18075892 Supplier Tocris Bioscience™ Supplier No. 3858/50

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Description

Potent aryl hydrocarbon receptor (AhR) antagonist

Potent aryl hydrocarbon receptor (AhR) antagonist (IC50 = 30 nM). Exhibits no AhR agonist-like activity (at concentrations up to 100 μM). Inhibits 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced AhR-dependent transcription in vitro and reduces TCDD-induced toxicity in vivo. Attenuates Th17 differentiation of naive CD4 T cells and promotes expansion of hematopoietic stem cells in vitro.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 301326-22-7
Molecular Formula C19H19N5O

Specifications

Quantity 50 mg
Formula Weight 333.39
Purity >98%
Molecular Weight (g/mol) 333.395
Chemical Name or Material CH 223191
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