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Thermo Scientific™ CellSensor™ SBE-bla HEK 293T Cell Line

Product Code. 10553074
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Quantity:
1 Vial
Unit Size:
Each
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Product Code. 10553074

Brand: Thermo Scientific™ K1550

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Description

Smad cell signaling is a critical pathway involved in cell growth and proliferation.

Smad cell signaling is a critical pathway involved in cell growth and proliferation. The CellSensor SBE-bla HEK 293T cell line is responsive to transforming growth factor-beta 1 (TGF-β1) and can be used to probe the Smad signaling pathway.The CellSensor SBE-bla HEK 293T cell line contains the β-lactamase reporter gene under the control of the Smad Binding Element (SBE). The SBE-bla construct was transduced into HEK 293T cells by lentivirus to obtain the cell line. Flow cytometry was used to isolate a clone responsive to TGF-β1 a dose response curve for this cell line using TGF-B1 is available in the validation packet data. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY

Specifications

Assay Entry Cell-based beta lactamase reporter gene
Cell State Dividing Cells
Content And Storage CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
For Use With (Application) Signaling Pathway
Product Line CellSensor
Quantity 1 Vial
Target Entry TGF beta/BMP pathway, TGF beta R
Type Cell Line
Cell Line HEK 293T
System Type CellSensor™
Druggable Target Signaling Pathway
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For Research Use Only. Not for use in diagnostic procedures.

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