CD73 Monoclonal Antibody (eBioTY/11.8 (TY/11.8)), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-0731-025

Product Code. 17111082

Description

eBioTY/11.8 recognizes the with CD73 a 69-kDa GPI-anchored cell-surface protein with ecto-5'-nucleotidase activity. Expression on myeloid cells (CD11b) is restricted to the bone marrow. In human CD73 can be induced to secrete a soluble form with IL-2 suggesting a role in mediating activation signals. Differences between human and mouse CD73 have been reported. BALB/c mice have more CD4+CD73+ than CD8+CD73+ while the reciprocal is documented in humans. CD73 is expressed on a subset of lymphocytes and increases during lymphocyte maturation. Recently it has been found that memory CD4 T cells express and are similar to the uncommitted primed precursor helper cells (Thpp) that can differentiate into Th1 or Th2 cells. Furthermore CD73 has been found on regulatory T cells.

CD73 Monoclonal antibody specifically detects CD73 in Mouse samples. It is validated for Control, Flow Cytometry, Functional Assay

Specifications

• Antigen: CD73
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: Q61503
• Host Species: Rat
• Quantity: 25 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Functional Assay
• Clone: eBioTY/11.8 (TY/11.8)
• Conjugate: Functional Grade
• Gene: NT5E
• Gene Alias: 2210401F01Rik; 5 nucleotidase, ecto; 5' nucleotidase, ecto; 5'-NT; 5'-nucleotidase; 5'-nucleotidase ecto; 5'-nucleotidase, ecto (CD73); AI447961; CALJA; CD73; E5NT; Ecto-5'-nucleotidase; eN; eNT; NT; Nt5; Nt5e; Nte; Purine 5-Prime-Nucleotidase
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23959
• Content And Storage: 4° C
• Form: Liquid