CD7 Mouse anti-Human, Clone: T3-3A1, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-54901-0.1MG

Product Code. 18259290

Description

CD7 Monoclonal specifically detects CD7 in Human samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunofluorescence, CyTOF-ready.

Specifications

• Antigen: CD7
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: 10mM PBS with No Preservative
• Gene Symbols: CD7
• Immunogen: Human T cells
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 40kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunofluorescence
• Clone: T3-3A1
• Dilution: Flow Cytometry 0.5 - 1ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Alias: CD7 antigen, CD7 antigen (p41), CD7 molecule, GP40T-cell surface antigen Leu-9, LEU-9, T-cell antigen CD7, T-cell leukemia antigen, Tp40, TP41p41 protein
• Host Species: Mouse
• Molecular Weight of Antigen: 40 kDa
• Quantity: 0.1 mg
• Research Discipline: Cytokine Research, Signal Transduction
• Gene ID (Entrez): 924
• Target Species: Human
• Form: Purified

For Research Use Only