Invitrogen™ CD6 Recombinant Rabbit Monoclonal Antibody (021), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA552416

Product Code. 30019586

Description

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Specifications

• Antigen: CD6
• Classification: Recombinant Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.05% BSA and 0.09% sodium azide
• Gene Accession No.: Q61003
• Gene Symbols: CD6
• Immunogen: Recombinant Mouse CD6 protein (Gly 17-Gly396).
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry
• Clone: 021
• Conjugate: PE
• Gene: CD6
• Gene Alias: Cd6; CD6 antigen; CD6 antigen, Tp120; Cd6 molecule; FLJ44171; OX52; Soluble CD6; T12; T-cell differentiation antigen CD6; TP120
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12511
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid