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CD5 Mouse, anti-Human, APC, Clone: UCHT2, STEMCELL Technologies
Mouse Monoclonal Antibody
£233.55 - £479.25
Specifications
| Antigen | CD5 |
|---|---|
| Clone | UCHT2 |
| Applications | Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Conjugate | APC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17188921
|
Stemcell Technologies
60082AZ.1 |
25 Tests |
£233.55
25 tests |
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|
17178921
|
Stemcell Technologies
60082AZ |
100 Tests |
£479.25
100 tests |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
- The UCHT2 antibody reacts with CD5, an ∼67 kDa single-chain type I glycoprotein and member of the scavenger receptor superfamily, which is constitutively expressed on thymocytes, T cells, B cell subsets, peripheral blood dendritic cells and some leukemia and lymphoma cells, including chronic B lymphocytic leukemia (B-CLL) cells
- CD5 is expressed at low levels on thymocytes and at high density on mature T cells
- Putative ligands include CD5L and CD72
- CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T cell/B cell interactions via its physical and functional associations with the T cell receptor/CD3 complex and the B cell receptor
- Studies with CD5 knockout mice indicate that CD5 negatively regulates antigen receptor-mediated signaling in thymocytes and mature T cells
- The UCHT2 antibody binds to epitope 2 located in the extracellular domain of CD5
Specifications
| CD5 | |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry | |
| APC | |
| Cynomolgus, Rhesus Monkey, Chimpanzee, Human | |
| Primary |
| UCHT2 | |
| Monoclonal | |
| Mouse | |
| IgG1 κ |
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