CD45.1 Mouse, anti-Mouse, Biotin, Clone: A20, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60117BT.1

Product Code. 17149141

Description

• The A20 monoclonal antibody reacts with mouse alloantigen CD45.1 (Ly5.1) expressed by all hematopoietic cells except mature erythrocytes and platelets in mouse strains RIII, SJL/J, STS/A, and DA
• Clone A20 does not react with leukocytes that express CD45.2 alloantigen
• CD45.1 is an allelic form of CD45 (leukocyte common antigen), a 180 - 240 kDa type I transmembrane glycoprotein
• CD45 is a member of the protein tyrosine phosphatase (PTP) family and functions in a number of immunoregulatory processes, including cell activation, growth, lymphocyte development, differentiation, and oncogenic transformation
• The isoforms of CD45 correlate to specific cell types, as well as specific activation and maturation states of immune cells
• The A20 monoclonal antibody has been used extensively in adoptive cell transfer and bone marrow transplantation studies in mice, allowing for the differentiation of CD45.2- and CD45.1- expressing cells

Specifications

• Antigen: CD45.1
• Classification: Monoclonal
• Conjugate: Biotin
• Quantity: 50 μg
• Target Species: Mouse
• Cell Type: Granulocytes and Subsets, Hematopoietic Stem and Progenitor Cells, Lymphocytes, Myeloid Cells

• Applications: Immunohistochemistry, Flow Cytometry, Immunofluorescence
• Clone: A20
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG2a κ