CD43 Mouse, anti-Human, APC, Clone: CD43-10G7, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60085AZ.1

Product Code. 17138941

Description

• The CD43-10G7 antibody reacts with human CD43, a type I transmembrane sialoglycoprotein expressed on the surface of most human hematopoietic cells, including thymocytes, peripheral T cells, NK cells, monocytes, granulocytes, some B cells (activated B cells and an early B cell subset in bone marrow), plasma cells, and hematopoietic progenitor cells
• Low expression levels are observed on platelets
• CD43 exhibits different glycoforms in the range of ∼95 - 135 kDa, depending on the cell type
• It binds ligands such as CD54 and CD169 (Siglec-1) and plays regulatory roles in cell adhesion and activation, apoptosis and tumor progression, and is used a marker for discriminating normal from neoplastic T cells and B cells within tissues
• Binding of the CD43-10G7 antibody to CD43 on neutrophils reportedly induces homotypic cell adhesion

Specifications

• Antigen: CD43
• Classification: Monoclonal
• Conjugate: APC
• Quantity: 25 Tests
• Target Species: Human
• Cell Type: B Cells

• Applications: Immunoprecipitation, Flow Cytometry, Functional Assay
• Clone: CD43-10G7
• Host Species: Mouse
• Primary or Secondary: Primary
• Isotype: IgG1 κ