CD3 Mouse anti-Human, Clone: UCHT1, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-0038-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15296737

Quantity Price
1 £ 60.53 / 100µg
EU Stock 14
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Description and Specification

Specification

Host Species Murine
Clone UCHT1
Format Purified
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Monoclonal or Polyclonal Monoclonal
Storage Requirements Store at 2-8°C.
Isotype IgG1
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD3
Quantity 100μg
Conjugate Unlabeled
Primary or Secondary Primary
Regulatory Status RUO
Gene Alias Leu-4, T3

The UCHT1 monoclonal antibody reacts with human CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR via immobilized UCHT1 initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.