CD271 (NGF Receptor) Monoclonal Antibody (ME20.4), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9400-95

Product Code. 17130742

Description

The MAb ME20.4 recognizes CD271, a 75 kDa type I transmembrane protein that belongs to the low-affinity neurotrophin receptor and tumor necrosis factor receptor superfamily. CD271 is expressed by neurons, Schwann cells, melanocytes, mesenchymal stem/stromal cells, neural crest stem cells, astrocytes, oligodendrocytes, and a subset of lymphoid cells including follicular dendritic cells. CD271 binds to the ligands NGF, BDNF, NTF3, and NTF4. CD271 contains a death domain which induces apoptosis and regulates cell growth and proliferation through interactions with TRAF2, TRAF4, TRAF6, PTPN13, and RANBP9. The ME20.4 MAb recognizes human, Non-human Primate, mouse, rat, sheep, rabbit, cat, dog, and pig CD271.

CD271 (NGF Receptor) Monoclonal antibody specifically detects CD271 (NGF Receptor) in Canine, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot

Specifications

• Antigen: CD271 (NGF Receptor)
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: P07174, P08138, Q9Z0W1
• Host Species: Mouse
• Quantity: 10 mg
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Non-human Primate, Ovine, Pig, Rabbit, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Clone: ME20.4
• Conjugate: Unconjugated
• Gene: Ngfr
• Gene Alias: CD271; CD271 antigen; Gp80-LNGFR; LNGFR; low affinity nerve growth factor receptor; low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); nerve growth factor receptor, fast; NGF receptor; NGFR; NGR; p75; p-75; p75 ICD; p75 neurotrophin receptor; p75 ntr; p75(NTR); p75NGFR; p75NTR; RNNGFRR; TNFR superfamily, member 16; TNFRSF16; TNR16; Tumor necrosis factor receptor superfamily member 16
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100349095, 100525607, 101119064, 18053, 24596, 4804, 491071
• Content And Storage: 4° C
• Form: Liquid