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CD2 Mouse, anti-Human, APC, Clone: RPA-2.10, STEMCELL Technologies
Mouse Monoclonal Antibody
POA - £480.60
Specifications
| Antigen | CD2 |
|---|---|
| Clone | RPA-2.10 |
| Applications | Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence |
| Classification | Monoclonal |
| Conjugate | APC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17138381
|
Stemcell Technologies
60007AZ.1 |
25 Tests |
£207.90
25 tests |
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|
17128381
|
Stemcell Technologies
60007AZ |
100 Tests |
£480.60
100 tests |
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|
17107601
|
Stemcell Technologies
100-0432 |
500 Tests | |||||||
Description
- The RPA-2.10 antibody reacts with CD2, an ∼50 kDa type I transmembrane glycoprotein and a member of the immunoglobulin (Ig) superfamily; two Ig-like domains are located in its extracellular portion
- CD2 is broadly expressed on peripheral T and NK cells, dendritic cells, erythrocytes, most thymic T cells, subsets of thymic B cells, and on the endothelium
- CD2 expression appears early during T cell differentiation
- Aberrant expression has been observed in some lymphomas and myeloid leukemias
- CD2 is critically important for T cell activation and signaling, as well as lymphocyte adhesion
- The primary ligand for CD2 is CD58 (LFA-3) located on antigen-presenting cells, with additional ligands comprising CD15 (SSEA-1), CD48 and CD59
- Notably, the RPA-2.10 antibody blocks the mixed lymphocyte reaction
Specifications
| CD2 | |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| APC | |
| Primary |
| RPA-2.10 | |
| Monoclonal | |
| Mouse |
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