CD150 Monoclonal Antibody (9D1), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-1501-025

Product Code. 17191152

Description

The 9D1 MAb reacts with mouse CD150, an ∽70 kDa transmembrane glycoprotein also known as Signaling Lymphocyte Activation Molecule (SLAM). CD150 is expressed by T (especially TH1) and B cells and its expression is rapidly upregulated on these cells upon activation. Immature thymocytes and dendritic cells also express this antigen. Signaling through SLAM in T cells induces proliferation and augmentation of the interferon-gamma response. Furthermore, SLAM is thought to play a role in adhesion between the T cell and antigen-presenting cell. 9D1 is reported to be an activating antibody. Mouse hematopoietic stem cells (HSC) can be identified using SLAM family markers, such as CD150+CD244-CD48-. For this application we recommend the use of antibody clone mShad150 (cat. 12-1502).

CD150 Monoclonal antibody specifically detects CD150 in Mouse samples. It is validated for Flow Cytometry, Functional Assay

Specifications

• Antigen: CD150
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative; pH 7.2
• Gene Accession No.: Q9QUM4
• Host Species: Rat
• Quantity: 25 mg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Functional Assay
• Clone: 9D1
• Conjugate: Functional Grade
• Gene: Slamf1
• Gene Alias: 4933415F16; AA177906; CD150; CD150 antigen; CDw150; ESTM51; IPO-3; RGD1560634; signaling lymphocyte activation molecule; signaling lymphocytic activation molecule; signaling lymphocytic activation molecule family member 1; Slam; SLAM family member 1; SLAMF1
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27218
• Content And Storage: 4° C
• Form: Liquid