CD132 Mouse anti-Human, PE, Clone: AG184, BD

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15841249	BD Biosciences 561699	25 μg
15848518	BD Biosciences 555900	0.2 mg

Description

TheAG184 monoclonal antibody specifically binds to the 65-70 kDa common γ subunit (γc) that is shared by the IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor complexes. The γc receptor is a type 1 transmembrane glycoprotein that is constitutively expressed by most peripheral T and B lymphocytes, NK cells, monocytes and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analyses, the AG184 antibody has been shown to specifically recognize human γc expressed by cell lines including human γc gene-transfected cell lines which are known to express the human γc chain. The AG184 antibody can bind the γc chain in the receptors complexed with IL-2, IL-4, or IL-7, indicating that the antibody recognizes an epitope which is distinct from the cytokine binding site of the γc chain.

Specifications

• Antigen: CD132
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Target Species: Human
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: IL2RG; IL-2RG; IL-2Rγ; Common gamma chain; γc; CIDX; SCIDX; SCIDX1; IMD4

• Clone: AG184
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.