Invitrogen™ Caspase 6 Monoclonal Antibody (C6), Invitrogen™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
17900043	Invitrogen™ MA551055	200 μL
17989612	Invitrogen™ MA551056	20 μL

Description

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

• Antigen: Caspase 6
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
• Gene Symbols: Casp6
• Isotype: IgG1 κ
• Purification Method: Protein A/G
• Gene: Casp6

• Clone: C6
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Bovine
• Gene Accession No.: Q3T0P5
• Gene ID (Entrez): 538409
• Immunogen: Recombinant Bovine CASP6 protein, Ala194-Asn293 (Accession #Q3T0P5).
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.