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DiscoverX cAMP Hunter™ eXpress PTGIR CHO-K1 GPCR Assay

Product Code. 17314469
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17314469

Brand: DiscoverX 950051E2CP2M

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This item is not returnable. View return policy

The cAMP Hunter™ eXpress PTGIR CHO-K1 GPCR Assay measures PTGIR (GPCR) activity via increased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™TM PTGIR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin I2, beraprost) based activation of PTGIR GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype PTGIR , a naturally Gs coupled GPCR. Upon activation of PTGIR , the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry CHO-K1
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist Beraprost
Quantity 200 dp (2 x 96-well)
Target Entry PTGIR
Cell Line CHO-K1
Target PTGIR
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