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DiscoverX cAMP Hunter™ eXpress PTGER3 CHO-K1 GPCR Assay

Product Code. 17324699
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17324699

Brand: DiscoverX 950159E2CP2M

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This item is not returnable. View return policy

Description

The cAMP Hunter™ eXpress PTGER3 CHO-K1 GPCR Assay measures PTGER3 (GPCR) activity via decreased levels of intracellular cAMP. eXpress kits contain all assay materials: cells, reagents, and plates.

The cAMP Hunter™ PTGER3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. prostaglandin E2, cloprostenol) based activation of PTGER3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype PTGER3 , a naturally Gi/Go coupled GPCR. Upon activation of PTGER3 , the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry CHO-K1
For Use With (Application) Assay-Ready eXpress Kits
Primary Agonist (+/-)-Cloprostenol sodium salt hydrate
Quantity 200 dp (2 x 96-well)
Target Entry PTGER3
Cell Line CHO-K1
Target PTGER3
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