Invitrogen™ C8A Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5145447

Product Code. 17968852

Description

C8A is a component of the complement system and contains three polypeptide subunits: alpha, beta and gamma. C8A, in particular, contains the alpha subunit of C8 and is a constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. Disease associated with C8A include Type 1 C8 deficiency and immunodeficiency due to C8A deficiency.

Specifications

• Antigen: C8A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C8A
• Gene Symbols: C8A
• Immunogen: Recombinant Rat C8a protein, Gln21-His300 (Accession #D3ZWD6).
• Quantity: 200 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Alias: C8a; complement component 8 alpha subunit; complement component 8 subunit alpha; complement component 8, alpha polypeptide; complement component C8 alpha chain
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 298288
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid