beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18107317	Novus Biologicals NBP2-47700-0.1MG	0.1 mg

Description

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence, CyTOF-ready.

Specifications

• Antigen: beta 2-Microglobulin
• Concentration: 1.0 mg/mL
• Applications: Flow Cytometry, Immunofluorescence, CyTOF
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
• Formulation: PBS with No Preservative
• Gene ID (Entrez): 567
• Immunogen: Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
• Primary or Secondary: Primary
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Molecular Weight of Antigen: 12 kDa

• Clone: 246-E9.E7 (same as HLA.ABC.m2)
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human, Primate (Negative)
• Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
• Gene Symbols: B2M
• Isotype: IgG2a κ
• Purification Method: Protein A or G purified
• Test Specificity: Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.