beta 2-Microglobulin Antibody (246-E9.E7 (same as HLA.ABC.m2)) - Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-47700-0.1MG

Product Code. 18107317

Description

beta 2-Microglobulin Monoclonal specifically detects beta 2-Microglobulin in Human, Primate (Negative) samples. It is validated for Flow Cytometry, Immunofluorescence, CyTOF-ready.

Specifications

• Antigen: beta 2-Microglobulin
• Classification: Monoclonal
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
• Gene Alias: beta chain of MHC class I molecules, beta-2-microglobin, beta-2-microglobulin
• Host Species: Mouse
• Molecular Weight of Antigen: 12 kDa
• Quantity: 0.1 mg
• Research Discipline: Adaptive Immunity, Cancer, Cell Biology, Diabetes Research, Immunology
• Gene ID (Entrez): 567
• Target Species: Human, Primate (Negative)
• Form: Purified

• Applications: Flow Cytometry, Immunofluorescence, CyTOF
• Clone: 246-E9.E7 (same as HLA.ABC.m2)
• Conjugate: Unconjugated
• Formulation: PBS with No Preservative
• Gene Symbols: B2M
• Immunogen: Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient.
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 12kDa, identified as beta-microglobulin. beta-microglobulin non-covalently associates with the 44kDa chain to form the HLA Class I antigen complex. Human beta-2 microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to human beta-2 microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of beta-2 microglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2a κ