Invitrogen™ ATF3 Recombinant Rabbit Monoclonal Antibody (24GB6930)

Rabbit Recombinant Monoclonal Antibody

Product Code	Brand	Quantity
30275583	Invitrogen™ MA556975	100 μL
30275802	Invitrogen™ MA556976	20 μL

Description

ATF3 Recombinant Monoclonal Antibody for Western Blot

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ATF3
• Concentration: 0.6 mg/mL
• Applications: Flow Cytometry, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P18847
• Gene ID (Entrez): 467
• Immunogen: Recombinant protein of human ATF3 (aa 1-181).
• Product Type: Antibody

• Clone: 24GB6930
• Content And Storage: -20°C
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: ATF3
• Gene Alias: activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526
• Gene Symbols: ATF3
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography