Invitrogen™ ATF3 Recombinant Rabbit Monoclonal Antibody (24GB6930)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA556976

Product Code. 30275802

Description

ATF3 Recombinant Monoclonal Antibody for Western Blot

ATF3 (Activating transcription factor 3) is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. It encodes a protein with a calculated molecular mass of 22 kD. ATF3 represses rather than activates transcription from promoters with ATF binding elements. An alternatively spliced form of ATF3 (ATF3 delta Zip) encodes a truncated form ATF3 protein lacking the leucine zipper protein-dimerization motif and does not bind to DNA. In contrast to ATF3, ATF3 delta Zip stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Three transcript variants encoding two different isoforms have been found for this gene.

Specifications

• Antigen: ATF3
• Classification: Recombinant Monoclonal
• Concentration: 0.6 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P18847
• Gene Symbols: ATF3
• Immunogen: Recombinant protein of human ATF3 (aa 1-181).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Western Blot
• Clone: 24GB6930
• Conjugate: Unconjugated
• Gene: ATF3
• Gene Alias: activating transcription factor 3; ATF 3; ATF3; cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3; Liver regeneration factor 1; Lrf1; LRF-1; LRFI; LRG-21; MGC137608 protein; transcription factor LRG-21; zgc:55526
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 467
• Content And Storage: -20°C
• Form: Liquid