Invitrogen™ ASCC2 Monoclonal Antibody (24GB6350)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA557346

Product Code. 30274923

Description

ASCC2 Monoclonal Antibody for Western Blot

Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). [UniProt].

Specifications

• Antigen: ASCC2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: ASCC2
• Gene Alias: 1700011I11Rik; 2610034L15Rik; activating signal cointegrator 1 complex subunit 2; AI482016; ASC-1 complex subunit P100; Asc1p100; ASCC2; AW046480; p100; RGD1561422; trip4 complex subunit p100
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 498402, 75452, 84164
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 24GB6350
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q91WR3, Q9H1I8
• Gene Symbols: ASCC2
• Immunogen: Recombinant protein of human ASCC2 (aa 1-757).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1