CD62L Mouse anti-Human, V450, Clone: DREG 56, BD

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
15870199	BD Biosciences 560441	30 Tests
15860199	BD Biosciences 560440	120 Tests

Description

Reacts with a 76-95kDa glycoprotein referred to as L-selectin or LECAM-1. CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. Dreg-56 antibody recognizes the same antigen as LAM-1, and specifically inhibits >90% of binding of human lymphocytes to high endothelial venules (HEV) in frozen sections of peripheral, but not mucosal lymphoid tissue. It thus defines L-selectin as a human lymphocyte homing receptor for peripheral lymph node HEV. The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406nm and has an Em Max at 450nm. Conjugates with BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

Host Species: Mouse
Clone: DREG-56
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD62L
• Applications: Flow Cytometry
• Conjugate: Violet Fluor 450 (V450)
• Regulatory Status: RUO
• Target Species: Human
• Immunogen: Supernatant from PMA-activated Human Peripheral Blood Leukocytes
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: DREG 56
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Immunology
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: SELL; L-selectin; LSEL; LAM-1; LECAM-1; LEU8; LNHR; MEL-14; PLNHR; TQ-1

For Research Use Only.