CD11c Hamster anti-Mouse, APC, Clone: HL3, BD

Hamster Monoclonal Antibody

Brand:  BD Biosciences 561119

Product Code. 15860789

Description

The HL3 antibody reacts with the integrin αx chain of gp150, 95 (CD11c/CD18) which is expressed on dendritic cells and CD4- CD8+ intestinal intraepithelial lymphocytes (IEL) and is upregulated on IEL and lymph-node T cells following in vivo activation. CD11c is also found on human NK cells. Although its expression on mouse NK cells is not published, we have detected CD11c on mouse splenic NK cells. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. CD11c plays a role in binding of iC3b.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Hamster
Clone: HL3
Isotype: IgG1 λ
Species Reactivity: Mouse
Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes

Flow Cytometry

Specifications

• Antigen: CD11c
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Cd11c; Itgax; Integrin alpha-X; Integrin αX; Cr4; Complement receptor 4
• Host Species: Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG1 λ2

• Applications: Flow Cytometry
• Clone: HL3
• Conjugate: APC
• Formulation: Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
• Immunogen: C57BL/6 Mouse Intestinal Intraepithelial Lymphocytes
• Quantity: 25 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.