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Bcl-X set Mouse, Unlabeled, Clone: 2H12, BD
Mouse Monoclonal Antibody
£236.00 - £394.53
Specifications
| Antigen | Bcl-X set |
|---|---|
| Clone | 2H12 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15866478
|
BD Biosciences
551020 |
50 μg | |||||||
|
15876478
|
BD Biosciences
551022 |
150 μg |
 £410.00 £394.53 / Each Save £15.47 3% Off |
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Description
Members of the Bcl-2 family play a major role in regulating the response of cells to a wide variety of apoptotic signals. Some Bcl-2 family members like Bcl-2, block apoptosis, whereas others promote apoptosis and inhibit Bcl-2 activity. Bcl-x is a Bcl-2 homologue that has two isoforms, resulting from alternative splicing. Bcl-xL (long) is a 241 amino acid protein (25-29 kDa) that is 47% homologous to Bcl-2 on the amino acid level. Bcl-xS (short) is a 178 amino acid protein (∼ 19.5 kDa) lacking a 63 amino acid domain that is well conserved among members of the Bcl-2 protein family. Bcl-xL blocks cell death, whereas Bcl-xS inhibits Bcl-2 and promotes cell death.Specifications
| Bcl-X set | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human, Mouse | |
| Primary | |
| Store undiluted at -20°C. |
| 2H12 | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| IgG2a | |
| Affinity Purified |
For Research Use Only.
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