Annexin II Light Chain Mouse, Unlabeled, Clone: 148, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 610071

Product Code. 15865239

Description

Annexin II often exists as a heterotetramer complexed with an 11kDa light chain. This p11 subunit is related to the S100 family of calcium-binding proteins but mutations have rendered it unable to bind calcium. The p11 protein binds to the amino terminus of the annexin II monomer, but not to other annexins. It may regulate the function of annexin II, as the tetrameric form seems to have a higher calcium and phospholipid-binding affinity than the monomeric annexin II. In the cell, p11 has been localized to the cytoplasmic face of the plasma membrane where the annexin II tetramer is known to exist.

Host Species: Mouse
Clone: 148
Isotype: IgG1
Species Reactivity: Human
Immunogen: Cow Annexin II Light Chain aa. 1-97
Formula Weight [Chemical]: 11kDa

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

• Antigen: Annexin II Light Chain
• Classification: Monoclonal
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Immunogen: Cow Annexin II Light Chain aa. 1-97
• Quantity: 150 μg
• Research Discipline: Cell Biology
• Target Species: Canine, Chicken, Human
• Isotype: IgG1

• Applications: Western Blot
• Clone: 148
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

For Research Use Only.