ANLN Mouse anti-Human, Clone: 1B4A8, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66643-1-IG-150UL

Product Code. 16818715

Description

ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.

Specifications

• Antigen: ANLN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q9NQW6
• Gene Symbols: ANLN
• Immunogen: ANLN Fusion Protein Ag19294
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: 1B4A8
• Conjugate: Unconjugated
• Gene: ANLN
• Gene Alias: Actin binding protein anillin, anillin, actin binding protein, ANLN, scra, Scraps
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 54443
• Content And Storage: -20°C
• Form: Liquid