Ampicillin sodium salt, Thermo Scientific™

Product Code	Brand	Quantity
15465979	Thermo Scientific Alfa Aesar J63807.06
15475979	Thermo Scientific Alfa Aesar J63807.09	10g

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• Ampicillin sodium salt is a semi-synthetic derivative of penicillin with a broad-spectrum antibacterial activity against several species, including Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Ralstonia solanacearum

• It can inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins, inhibiting peptidoglycan synthesis, which is an essential component of the bacterial cell wall

Application

• Ampicillin sodium salt has been used as a reagent for transformed cells that express β-lactamase

• It can be used to select for ampicillin resistance in mutated and transformed cells

• Ampicillin sodium salt acts as a structural analog of acyl-D-alanyl-D-alanine, acylates the transpeptidase enzyme preventing the cross-linking of the cell wall peptidoglycan, which is necessary for the growth of the bacterium

Chemical Identifiers

• CAS: 69-52-3
• Molecular Weight (g/mol): 374.411
• InChI Key: BSFVNXCYXDYHOD-ZQDFAFASSA-N
• IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;molecular hydrogen;sodium

• Molecular Formula: C16H21N3NaO4S
• MDL Number: MFCD00064313
• PubChem CID: 131673879
• SMILES: [HH].CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.[Na]

Specifications

• CAS: 69-52-3
• Molecular Formula: C16H21N3NaO4S
• Beilstein: 4119211
• Solubility Information: Freely soluble in water; Sparingly soluble in acetone
• SMILES: [HH].CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C.[Na]
• Molecular Weight (g/mol): 374.411
• Formula Weight: 371.39

• Color: White
• MDL Number: MFCD00064313
• Merck Index: 14,586
• InChI Key: BSFVNXCYXDYHOD-ZQDFAFASSA-N
• IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;molecular hydrogen;sodium
• PubChem CID: 131673879
• Chemical Name or Material: Ampicillin sodium salt

Safety and Handling

GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.

P260-P271-P272-P280g-P285-P302+P352-P304+P340-P314-P333+P313-P342+P311-P363-P501c

H317-H334

missing translation for 'einecsNumber' : 200-708-1

missing translation for 'rtecsNumber' : XH8400000

missing translation for 'tsca' : No

Recommended Storage : Keep cold

RUO – Research Use Only