Invitrogen™ ADCY6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
17740344	Invitrogen™ PA5118931	200 μL
17713674	Invitrogen™ PA5122273	20 μL

Description

ADCY6 Polyclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita.

Specifications

• Antigen: ADCY6
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human, Mouse
• Gene: ADCY6
• Gene Alias: AC6; ACVI; Adcy6; ADCYB; adenylate cyclase 6; adenylate cyclase type 6; Adenylate cyclase type VI; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase; DKFZp779F075; KIAA0422; LCCS8; mKIAA0422
• Gene Symbols: ADCY6
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.5 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: O43306, Q01341
• Gene ID (Entrez): 112, 11512
• Immunogen: Recombinant protein Adenylate Cyclase 6. The antigen corresponds to amino acid range 314-501 of the target protein.
• Product Type: Antibody