ACVRL1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16883544	Proteintech 14745-1-AP-20UL	20 μL
16873544	Proteintech 14745-1-AP-150UL	150 μL

Description

The TGF-beta superfamily of ligands exerts its biological activity by binding to heteromeric receptor complexes two types (I and II) of the serine/threonine kinases. ALK1, like the other type I receptors, contains a cysteine rich domain with conserved cysteine spacing in the extracellular region and a glycine and serine rich domain preceding the kinase domain. The reduced human ALK1 monomer has a calculated molecular mass of approximately 37.3 kDa. Due to glycoslyation, the recombit human protein migrates as a 50-55 kDa protein in SDS-PAGE under reducing conditions. Human and mouse ALK1 share approximately 71% amino acid sequence identity in their extracellular domains. ALK1 is highly expressed in endothelial cells and other vascular tissues.

Specifications

• Antigen: ACVRL1
• Applications: Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Flow Cytometry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P37023
• Gene ID (Entrez): 94
• Immunogen: ACVRL1 Fusion Protein Ag6449
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: ACVRL1

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I
• Gene Symbols: ACVRL1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody