ACTN2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 14221-1-AP-20UL

Product Code. 16892754

Description

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.

Specifications

• Antigen: ACTN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ACTN2
• Gene Alias: actinin, alpha 2, ACTN2, Alpha actinin 2, CMD1AA, F actin cross linking protein
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11472, 291245, 88
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunoprecipitation
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P35609, Q9JI91
• Gene Symbols: Actn2
• Immunogen: ACTN2 Fusion Protein Ag5459
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG