4',5,7-Trihydroxyflavone, 97%

Product Code.	Quantity	Unit Size
11358126	25 mg	25mg
11368126	100 mg	100mg

Product Code. 11358126 Supplier Thermo Scientific Alfa Aesar Supplier No. L15041.MB

Description

CAS: 520-36-5 | C15H10O5 | 270.24 g/mol

4',5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4′,5,7-Trihydroxyflavone is a nonmutagenic flavonoid shown to inhibit cell proliferation, angiogenesis and protein kinase. Also induces apoptosis in breast cancer cells. It inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Solubility
Soluble in dimethyl sulfoxide (27 mg/ml) or 1M potassium hydroxide (50mg/ml).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with and strong oxidizing agents.

Especificaciones

Identificadores de productos químicos

• CAS: 520-36-5
• Molecular Formula: C15H10O5
• Molecular Weight (g/mol): 270.24
• MDL Number: MFCD00006831
• InChI Key: KZNIFHPLKGYRTM-UHFFFAOYSA-N
• Synonym: apigenin, 5,7-dihydroxy-2-4-hydroxyphenyl-4h-chromen-4-one, chamomile, spigenin, versulin, apigenol, 4',5,7-trihydroxyflavone, apigenine, c.i. natural yellow 1, 5,7,4'-trihydroxyflavone
• PubChem CID: 5280443
• ChEBI: CHEBI:18388
• IUPAC Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
• SMILES: OC1=CC=C(C=C1)C1=CC(=O)C2=C(O)C=C(O)C=C2O1

• Melting Point: ∽315°C (decomposition)
• Quantity: 25 mg
• Beilstein: 262620
• Merck Index: 14,730
• Solubility Information: Soluble in dimethyl sulfoxide (27mg/ml) or 1M potassium hydroxide (50mg/ml).
• Formula Weight: 270.24
• Percent Purity: 97%
• Chemical Name or Material: 4',5,7-Trihydroxyflavone

Seguridad y manipulación

Nombre del producto

• 4',5,7-Trihydroxyflavone

Palabra de advertencia

• Warning

Clasificación

• Serious eye damage/eye irritation Category 2
• Skin corrosion/irritation Category 2
• Specific target organ toxicity Category 3

Indicaciones de peligro

• H315-Causes skin irritation.
• H319-Causes serious eye irritation.
• H335-May cause respiratory irritation.

Consejos de prudencia

• P280-Wear protective gloves/protective clothing/eye protection/face protection.
• P302+P352-IF ON SKIN: Wash with plenty of water/soap.
• P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
• P312-Call a POISON CENTER/doctor/if you feel unwell.
• P332+P313-If skin irritation occurs: Get medical advice/attention.
• P337+P313-If eye irritation persists: Get medical advice/attention.

Otros peligros

• MIXTURE LIST-Contain: 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzo pyrone

SDS

RUO – Research Use Only