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DiscoverX PathHunter™ eXpress TORC2 Nuclear Translocation Assay

Product Code. 17303839
Encompass
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Quantity:
200 dp (2 x 96-well)
Unit Size:
1 set
This item is not returnable. View return policy

Product Code. 17303839

Brand: DiscoverX 930813E3CP19M

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This item is not returnable. View return policy

The PathHunter™ eXpress TORC2 Nuclear Translocation Assay measures CRTC/CREB pathway activation via nuclear translocation of TORC2. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ eXpress TORC2 Nuclear Translocation Assay provides an easy-to-use cell based assay to study drug candidates affecting the CRTC/CREB pathway. This kit assesses ligand (e.g. forskolin) based pathway activation via detection of resulting TORC2 (CRTC2) nuclear translocation. This product uses EFC technology. The included cells overexpress PL-tagged TORC2 (CRTC2) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC2 leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Assay Entry Pathway
For Use With (Application) Assay-Ready eXpress Kits
Quantity 200 dp (2 x 96-well)
Target Entry TORC2 (CRTC2)
Target TORC2 (CRTC2)
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