14-3-3 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 2E10A3, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66061-1-IG-20UL

Product Code. 16877595

Description

66061-1-Ig recognizes 14-3-3 tau (YWHAQ), eta (YWHAH), and zeta (YWHAZ), but not epsilon (YWHAE).

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5′ UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.

Specifications

• Antigen: 14-3-3
• Classification: Monoclonal
• Concentration: 0.71 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P27348, P68254, P68255
• Gene Symbols: Ywhaq
• Immunogen: 14-3-3 Fusion Protein Ag6055
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Porcine, Mouse, Rat, Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Flow Cytometry, Immunofluorescence
• Clone: 2E10A3
• Conjugate: Unconjugated
• Gene: YWHAQ
• Gene Alias: 14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 14-3-3 tau, HS1, Protein HS1, YWHAQ
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 100048964, 10971, 22630, 25577
• Content And Storage: -20°C
• Form: Liquid