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  5. Tocris Bioscience™ 10-DEBC hydrochloride

Tocris Bioscience™ 10-DEBC hydrochloride

Product Code. 18095072
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18095072 10 mg 10mg
18023822 50 mg 50mg
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Product Code. 18095072 Supplier Tocris Bioscience™ Supplier No. 2558/10

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Description

Selective Akt/PKB inhibitor

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 925681-41-0
Molecular Formula C20H26Cl2N2O

Specifications

Quantity 10 mg
Formula Weight 381.34
Purity >99%
Molecular Weight (g/mol) 381.341
Chemical Name or Material 10-DEBC hydrochloride
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