1,1-Dimethylbiguanide hydrochloride, Thermo Scientific™

1,1-Dimethylbiguanide hydrochloride (metformin hydrochloride, CAS # 115-70-4) is the salt of methylated biguanide, a compound exhibiting anti-hyperglycemic properties.

Brand:  Thermo Scientific Alfa Aesar J63361.06

Product Code. 15485609

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

General Description

• 1,1-Dimethylbiguanide consists of two guanidines with methyl substitutions at position 1

• 1,1-Dimethylbiguanide hydrochloride inhibits complex I of the mitochondrial respiratory chain, increasing AMP and activating target genes

• 1,1-Dimethylbiguanide hydrochloride enhances insulin sensitivity and fatty acid oxidation in cells

• 1,1-Dimethylbiguanide hydrochloride may also have antineoplastic action through the mammalian target of rapamycin pathway

• It is suitable for the laboratory research of diabetes, obesity, and related metabolic disorders

• It is also useful for the laboratory study of mammalian target of rapamycin (mTOR) pathways and AMPK ratios within the cell

Chemical Identifiers

• CAS: 1115-70-4
• Molecular Weight (g/mol): 165.63
• InChI Key: OETHQSJEHLVLGH-UHFFFAOYSA-N
• PubChem CID: 14219
• SMILES: [H+].[Cl-].CN(C)C(=N)N=C(N)N

• Molecular Formula: C4H12ClN5
• MDL Number: MFCD00012582
• Synonym: metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
• IUPAC Name: hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride

Specifications

• CAS: 1115-70-4
• Linear Formula: NH₂C(=NH)NHC(=NH)N(CH₃)₂·HCl
• Quantity: 5g
• Synonym: metformin hydrochloride, 1,1-dimethylbiguanide hydrochloride, metformin hcl, glucophage, riomet, diabefagos, meguan, metformin monohydrochloride, benofomin, denkaform
• InChI Key: OETHQSJEHLVLGH-UHFFFAOYSA-N
• IUPAC Name: hydrogen 1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide chloride
• PubChem CID: 14219
• Chemical Name or Material: 1,1-Dimethylbiguanide hydrochloride

• Molecular Formula: C4H12ClN5
• MDL Number: MFCD00012582
• Merck Index: 14,5938
• Solubility Information: Soluble in water (50mg/ml),ethanol,and DMSO (50 mM).
• SMILES: [H+].[Cl-].CN(C)C(=N)N=C(N)N
• Molecular Weight (g/mol): 165.63
• Formula Weight: 165.62