CAS RN 909910-43-6
CAS RN 909910-43-6
IUPAC Name:
3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamide
Synonyms:
3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)pyrazole-1-carbothioamide
Molecular Weight (g/mol):
421.52
Molecular Formula:
C25H19N5S
InChi Key:
HIJMSZGHKQPPJS-UHFFFAOYSA-N
SMILES:
CC1=CC=CC(=N1)C1=NN(C=C1C1=C2C=CC=CC2=NC=C1)C(=S)NC1=CC=CC=C1
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A 83-01, TRC
CAS: 909910-43-6 Molecular Formula: C25 H19 N5 S Molecular Weight (g/mol): 421.52 Synonym: A 83-01,3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide IUPAC Name: 3-(6-methyl-2-pyridyl)-N-phenyl-4-(4-quinolyl)pyrazole-1-carbothioamide SMILES: Cc1cccc(n1)c2nn(cc2c3ccnc4ccccc34)C(=S)Nc5ccccc5
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Tocris Bioscience™ A 83-01
A 83-01 synthesized to Ancillary Material Grade
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A 83-01, MedChemExpress
MedChemExpress A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.
