A 83-01, MedChemExpress

Product Code.	Quantity	unitSize
16463968	10 mg	10mg
16410327	50 mg	50mg

Product Code. 16463968

Brand: Medchem Express HY10432

Description

MedChemExpress A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.

A 83-01 is a potent inhibitor of TGF-β type I receptor ALK5 kinase, type I nodal receptor ALK4 and type I nodal receptor ALK7, with IC50s of 12 nM, 45 nM and 7.5 nM against the transcription induced by ALK5, ALK4 and ALK7, respectively.

Specifications

• Chemical Name or Material: A 83-01
• CAS: 909910-43-6
• Color: Off-White
• Purity Grade Notes: Research
• Molecular Formula: C₂₅H₁₉N₅S
• Quantity: 10 mg
• Solubility Information: DMSO : 25 mg/mL (59.31 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (insoluble)
• SMILES: S=C(N1N=C(C2=NC(C)=CC=C2)C(C3=CC=NC4=CC=CC=C34)=C1)NC5=CC=CC=C5
• Molecular Weight (g/mol): 421.52
• Formula Weight: 421.52
• Percent Purity: 95.0%
• Grade: Research
• Physical Form: Powder
• For Use With (Application): Cancer-Kinase/protease

Research purposes only