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CAS RN 208255-80-5

CH3ONHOOCH3H3CCH3HNOFF

CAS RN 208255-80-5

IUPAC Name: tert-butyl 2-{2-[2-(3,5-difluorophenyl)acetamido]propanamido}-2-phenylacetate
Synonyms: tert-butyl 2-{2-[2-(3,5-difluorophenyl)acetamido]propanamido}-2-phenylacetate
Molecular Weight (g/mol): 432.47
Molecular Formula: C23H26F2N2O4
InChi Key: DWJXYEABWRJFSP-UHFFFAOYNA-N
SMILES: CC(NC(=O)CC1=CC(F)=CC(F)=C1)C(=O)NC(C(=O)OC(C)(C)C)C1=CC=CC=C1
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DAPT

EDGE
2
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Tocris Bioscience™ DAPT
GREENER_CHOICE

CAS: 208255-80-5 Molecular Formula: C23H26F2N2O4

CAS 208255-80-5
Molecular Formula C23H26F2N2O4
3

Tocris Bioscience™ DAPT
GREENER_CHOICE

DAPT synthesized to Ancillary Material Grade

4

DAPT, MedChemExpress

MedChemExpress DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 432.46
Color White
Physical Form Solid
Chemical Name or Material DAPT
Grade Research
SMILES FC1=CC(F)=CC(CC(N[C@H](C(N[C@H](C(OC(C)(C)C)=O)C2=CC=CC=C2)=O)C)=O)=C1
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.62%
CAS 208255-80-5
Solubility Information DMSO : 62.5 mg/mL (144.52 mM; Need ultrasonic) ∣Ethanol : 10 mg/mL (23.12 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H335
Synonym GSI-IX
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H26F2N2O4
Formula Weight 432.46
5

STEMCELL Technologies DAPT

Notch pathway inhibitor; Inhibits γ-secretase

ENCOMPASS_PREFERRED