DAPT

Product Code. 15467109

Brand: Thermo Scientific Alfa Aesar J65864.MA

Description

CAS: 208255-80-5 | C23H26F2N2O4 | 432.468 g/mol

DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth, angiogenesis, and differentiation of human induced pluripotent stem cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
DAPT is used in the study of β-amyloid formation. DAPT has been shown to inhibit Notch signaling in studies of autoimmune and lymphoproliferative diseases, such as ALPS and lupus erythematosus, as well as in cancer cell growth,

Specifica

• CAS: 208255-80-5
• Color: White
• Molecular Formula: C23H26F2N2O4
• MDL Number: MFCD04974585
• Quantity: 10 mg
• Sensitivity: Light Sensitive
• Synonym: dapt, dapt gsi-ix, gamma-secretase inhibitor ix, gsi-ix, insolution gamma-secretase inhibitor ix, s-tert-butyl 2-s-2-2-3,5-difluorophenyl acetamido propanamido-2-phenylacetate, n-n-3,5-difluorophenacetyl-l-alanyl-s-phenylglycine t-butyl ester, tert-butyl 2s-2-2s-2-2-3,5-difluorophenyl acetamido propanamido-2-phenylacetate, tert-butyl 2s-2-2s-2-2-3,5-difluorophenyl acetyl amino propanoyl amino-2-phenylacetate, gsiix
• Solubility Information: Soluble in DMSO,ethanol,dichloromethane,DMF.
• InChI Key: DWJXYEABWRJFSP-XOBRGWDASA-N
• SMILES: CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F
• IUPAC Name: tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate
• Molecular Weight (g/mol): 432.468
• PubChem CID: 5311272
• ChEBI: CHEBI:86193
• Formula Weight: 432.5
• Physical Form: Lyophilized
• Chemical Name or Material: DAPT

Sicurezza e movimentazione

SDS

RUO – Research Use Only