CAS RN 1936422-33-1

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GNE-781, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pricing and Availability

GNE-781, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pricing and Availability

GNE-781, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

Pricing and Availability

MedChemExpress GNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	525.59
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GNE-781
Grade	Research
SMILES	O=C(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)NC
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.19%
CAS	1936422-33-1
Solubility Information	DMSO : 100 mg/mL (190.26 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₂₇H₃₃F₂N₇O₂
Formula Weight	525.59

CAS RN 1936422-33-1

CAS RN 1936422-33-1

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