CAS RN 1936421-41-8

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GNE-049, MedChemExpress

MedChemExpress GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.

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Specifications

Molecular Weight (g/mol)	510.58
Color	Yellow
Physical Form	Solid
Chemical Name or Material	GNE-049
Grade	Research
SMILES	CC(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	1936421-41-8
Solubility Information	DMSO : 100 mg/mL (195.86 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₂₇H₃₂F₂N₆O₂
Formula Weight	510.58

CAS RN 1936421-41-8

CAS RN 1936421-41-8

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