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GNE-049, MedChemExpress

Product Code. 16445156
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Product Code. 16445156 Supplier Medchem Express Supplier No. HY108435

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Description

MedChemExpress GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.

GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively.

Specifications

Chemical Name or Material GNE-049
Physical Form Solid
CAS 1936421-41-8
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C27H32F2N6O2
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 100 mg/mL (195.86 mM; Need ultrasonic)
SMILES CC(N1CCC(N(C2CCOCC2)N=C3N4CCCC5=C4C=C(C(F)F)C(C6=CN(C)N=C6)=C5)=C3C1)=O
Molecular Weight (g/mol) 510.58
Formula Weight 510.58
Percent Purity 98.0%
Grade Research
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Research purposes only

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