accessibility menu, dialog, popup

UserName

CAS RN 193275-84-2

CAS RN 193275-84-2

IUPAC Name: —
Synonyms: —
Molecular Weight (g/mol): —
Molecular Formula: —
InChi Key: —
SMILES: —
Molecular Weight (g/mol) 
  • (5)
Quantity 
  • (2)
  • (1)
  • (1)
  • (1)
Grade 
  • (2)
Percent Purity 
  • (2)
Physical Form 
  • (2)

Filtered Search Results

Products from some of our suppliers do not display in filtered search results. Please clear all filters to see these products.

Narrow Results

Narrow Results

category

brands

  • (2)
  • (2)
  • (3)

special programs

  • (2)
  • (2)

Molecular Weight (g/mol)

  • (5)

Quantity

  • (2)
  • (1)
  • (1)
  • (1)

Grade

  • (2)

Percent Purity

  • (2)

Physical Form

  • (2)
1 – 3 of 3 results
1

Tocris Bioscience™ Lonafarnib
GREENER_CHOICE

Potent farnesyl transferase inhibitor

CAS 193275-84-2
Chemical Name or Material 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
Recommended Storage Store at -20°C
Molecular Formula C27H31Br2ClN4O2
Formula Weight Observed MW: 638.82
Assay Percent Range >98%
2

Lonafarnib, TRC

CAS: 193275-84-2 Chemical Name or Material: Lonafarnib Formula Weight: 636.0502 InChI Formula: InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1 IUPAC Name: 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[1,2]cyclohepta[2,4-b]pyridin-11-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide Molecular Formula: C27 H31 Br2 Cl N4 O2 Molecular Weight (g/mol): 638.82 Recommended Storage: 4°C SMILES: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1 Synonym: 1-Piperidinecarboxamide, 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-,4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide,Lonafarnib,Sarasar,Sch 66336,Zokinvy

CAS 193275-84-2
Molecular Weight (g/mol) 638.82
InChI Formula InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
Chemical Name or Material Lonafarnib
Synonym 1-Piperidinecarboxamide, 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-,4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide,Lonafarnib,Sarasar,Sch 66336,Zokinvy
SMILES NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@H]3c4ncc(Br)cc4CCc5cc(Cl)cc(Br)c35)CC1
Recommended Storage 4°C
Molecular Formula C27 H31 Br2 Cl N4 O2
IUPAC Name 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[1,2]cyclohepta[2,4-b]pyridin-11-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide
Formula Weight 636.0502
3

Lonafarnib, MedChemExpress

MedChemExpress Lonafarnib (Sch66336) is a potent and orally active farnesyl transferase (FTase) inhibitor. Lonafarnib inhibits the activities of H-ras, K-ras and N-ras with IC50 values of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Lonafarnib also has anti-hepatitis delta virus (HDV) activities.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 638.82
Color White
Physical Form Solid
Chemical Name or Material Lonafarnib
Grade Research
SMILES O=C(N1CCC(CC(N2CCC([C@@H]3C4=C(Br)C=C(Cl)C=C4CCC5=CC(Br)=CN=C53)CC2)=O)CC1)N
For Use With (Application) Cancer-programmed cell death
Percent Purity 98.0%
CAS 193275-84-2
Solubility Information DMSO : 50 mg/mL (78.27 mM; Need ultrasonic)
Health Hazard 1 H315∣H319∣H335
Synonym Sch66336
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C27H31Br2ClN4O2
Formula Weight 638.82